Stray Cats' Brian Setzer returns to Tonight Show stage after autoimmune diagnosis left him unable to play guitar

Brian Setzer performed "Rock This Town" with the Stray Cats on The Tonight Show Starring Jimmy Fallon on August 18, 2026, per Billboard. In early 2025, Setzer revealed an autoimmune diagnosis that left him unable to play guitar; he sought treatment at the Mayo Clinic. The Fallon appearance marked the band's return to U.S. late-night television. NBC published the segment on its YouTube channel the same day.