Djokovic suffers earliest Cincinnati exit in 20 years, beaten by world No. 50 Tirante

Novak Djokovic lost 2-6 6-4 6-4 to Argentina's Thiago Tirante in the Cincinnati Open second round on August 15. Tirante, ranked a career-high No. 50, called it "the best win of my career." Djokovic, a three-time champion and third seed, had never failed to reach at least the last 32 in Cincinnati since his 2005 debut. The 39-year-old struggled visibly with the Ohio heat, taking a medical timeout after appearing to vomit courtside. His first match since the Wimbledon semi-finals ends his US Open build-up early.